Whole-genome sequencing for preventive
and precision adult care
The PRECISOCARE® Adult Program delivers comprehensive genomic evaluation for working-age adults — mapping hereditary disease risk, identifying pharmacogenomic safety factors, and enabling precision preventive medicine before conditions become clinically apparent.
Clinical indications for adult WGS
PRECISOCARE® adult whole-genome sequencing covers a broad spectrum of clinical applications — from proactive wellness genomics to targeted diagnostic evaluation.
Hereditary Cancer Screening
Identification of pathogenic variants in BRCA1/2, Lynch syndrome genes, TP53 (Li-Fraumeni), APC, PALB2, and 60+ additional hereditary cancer genes. Results inform surveillance protocols, risk-reduction surgery decisions, and cascade family testing.
Pharmacogenomics (PGx)
Comprehensive drug-gene interaction profiling across CYP2D6, CYP2C19, CYP2C9, DPYD, TPMT, UGT1A1, and others. Identifies poor metabolizers, ultra-rapid metabolizers, and high-risk drug combinations before prescribing or adverse event.
Cardiovascular Genomics
Hereditary cardiomyopathy (HCM, DCM, ARVC), channelopathies (long QT, Brugada, CPVT), familial hypercholesterolemia (FH), and aortopathy variants (Marfan, Loeys-Dietz). Informs cardiac surveillance, ICD candidacy, and statin therapy decisions.
Neurological Risk Profiling
Hereditary neurodegenerative conditions including familial ALS, early-onset Parkinson variants (LRRK2, PINK1), hereditary spastic paraplegia, and CADASIL. Informs neurological surveillance and family counseling for at-risk individuals.
Connective Tissue & Metabolic
Marfan syndrome, Ehlers-Danlos, Wilson disease, hereditary hemochromatosis, alpha-1 antitrypsin deficiency, and familial hypercholesterolemia. Many remain undiagnosed until complications occur — WGS enables pre-symptomatic identification.
Reproductive & Family Planning
Carrier status evaluation for autosomal recessive conditions, X-linked conditions, and structural variant identification relevant to reproductive decision-making. Results integrated with genetic counseling for family planning guidance.
Why PGx matters for every adult patient
Approximately 1 in 4 adults carries a clinically actionable pharmacogenomic variant that affects how they metabolize common medications. Standard prescribing practices do not account for these differences — leading to preventable adverse drug reactions, treatment failures, and medication non-response.
PRECISOCARE® includes comprehensive PGx profiling with every adult WGS order. Results are reported in a provider-ready format that maps directly to prescribing decisions, with drug-gene interaction guidance aligned to CPIC and FDA pharmacogenomic labeling.
Order a KitPractitioner education & genetic counseling
PRECISO provides structured genomics education for providers ordering adult WGS, with genetic counseling available for complex results, family cascade testing, and reproductive counseling.
Ordering Education
Structured education on adult WGS indications, pre-test counseling best practices, and how to position genomic testing within preventive care workflows.
Report Interpretation
Provider-ready report format with prioritized findings, clinical significance classification, and recommended next steps at the point of care — no specialist required for routine results.
Genetic Counseling Access
Board-certified genetic counselors available for complex variant interpretation, family communication support, and reproductive counseling when clinical complexity warrants escalation.
Connect your adult patients to precision genomic care
PRECISOCARE® Adult Program integrates into primary care, internal medicine, cardiology, oncology, and preventive medicine workflows. Order a kit or speak with our clinical team.