Senior Program | PrecisoCare®
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Senior Program
Ages 65+
Complex Care

Precision genomics for complex, aging, and high-risk populations

The PRECISOCARE® Senior Program addresses the unique genomic clinical needs of patients 65 and older — where polypharmacy, late-onset hereditary conditions, cognitive aging, and multi-system complexity require a more sophisticated diagnostic and care coordination approach.

Polypharmacy PGx optimization Cognitive aging markers CLIA / CAP Labs
40%
Of adults 65+ take 5 or more medications — polypharmacy PGx is critical
Late
Many hereditary conditions first present clinically after age 60
APOE
Cognitive risk variants inform monitoring protocols and care planning
1 Test
WGS replaces multiple targeted panels — comprehensive in a single draw
Program Focus Areas

Clinical applications in senior genomic medicine

Senior patients present with compounding genomic considerations that span medication safety, late-onset hereditary conditions, aging-related disease risk, and complex care coordination needs.

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Polypharmacy PGx Optimization

Senior patients often take 5–10+ medications simultaneously. PRECISOCARE® PGx profiling identifies drug-gene interactions across the full medication burden — providing prescribing guidance that accounts for combined effects, not just individual drug metabolism.

Clinical significance

Adverse drug reactions are among the leading causes of preventable hospitalization in adults 65+. PGx-guided prescribing has been shown to reduce adverse events and improve medication adherence in complex care populations.

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Cognitive Aging & Neurological Risk

Genomic profiling for APOE ε4 (Alzheimer's risk), LRRK2/GBA Parkinson variants, and other late-onset neurological conditions. Results inform monitoring frequency, preventive intervention timing, and advance care planning conversations.

Counseling note

Cognitive risk variants require pre-test and post-test genetic counseling to ensure patients and families can properly contextualize and act on results. PRECISOCARE® genetic counseling is available for all senior program participants.

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Late-Onset Cardiovascular Risk

Hereditary cardiomyopathy variants (including TTR amyloidosis — increasingly recognized as an underdiagnosed cause of heart failure in seniors), familial hypercholesterolemia, and arrhythmia predisposition. Informs cardiac surveillance intensity and treatment approach.

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Late-Onset Hereditary Cancer

Many BRCA, Lynch syndrome, and other hereditary cancer variants first present with clinical cancer diagnoses in the 6th–8th decade. Genomic evaluation of senior cancer patients — and their first-degree relatives — can identify hereditary etiology and guide family cascade testing.

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Bone & Immune Aging Markers

Hereditary osteoporosis risk variants, immune aging genomic markers, and connective tissue variants with late-onset manifestations. Results inform monitoring protocols and guide preventive interventions in high-risk senior populations.

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Complex Care Population Support

For seniors in skilled nursing, memory care, or high-acuity settings — PRECISOCARE® provides structured genomic infrastructure that integrates into care team workflows and supports multi-disciplinary clinical decision-making at scale.

Care Coordination

Supporting complex senior care teams

Senior patients typically have multiple providers — primary care, specialists, pharmacists, and care coordinators — who each benefit from genomic context. PRECISOCARE® delivers reports in a format designed for multi-provider clinical environments, not just single-episode care.

PHIN®-enabled connectivity ensures genomic findings and PGx results are accessible across the care continuum — so the patient's cardiologist, geriatrician, and pharmacist can all operate with the same genomic context without redundant testing.

Longitudinal genomic record accessible across care settings
PGx results persist and update as medication regimens change
Genetic counseling available for family communication and cascade testing
Structured reporting compatible with multi-disciplinary care team review
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Primary care integration PGx and risk results delivered in primary care-friendly format for routine application
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Cardiology & geriatrics Cardiovascular and aging-specific variant reporting aligned to specialist workflow
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Family & advance care planning Cognitive and late-onset condition results support advance directive conversations
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Institutional deployment Designed to scale across senior living, memory care, and integrated delivery networks

Deploy precision genomics across your senior care population

Whether you serve seniors through primary care, geriatrics, cardiology, or institutional care settings — PRECISOCARE® can be structured to meet your program needs.